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S2C12 cover.png

"The Serpent has risen. After feeding upon the fear and terror that continues to spread unchecked, a fully-powered Cul Borson now walks the Earth, threatening its very existence. Having eliminated the minor threats, the Serpent and the Worthy have turned their focus to S.H.I.E.L.D.
With pleas to Asgard going unanswered, Midgard must fend for itself or succumb to the Serpent.
"
— Chapter Briefing

Mission 1 - The Worthy Appeal
Mission 2 - Time Trials
Epic  Mission 3 - Serpent Strike
Chapter Mastery


Mission 1 - The Worthy Appeal

The Worthy Appeal
S2 C12 M1.png
Team
Up:
Iconbg.pngHawkeye Icon 1.png  Iconbg.pngHellcat Icon 1.png
Heroic Battle Task Icon.png Iconbg.pngUnknown Hero
Hero Deploys Iconbg.pngUnknown Hero

"Backed by the Serpent, the Worthy have set their sights on New York. Our heroes make a final attempt to connect with their former friends and allies before the final battle."
— Mission Preview

Unlock Requirements: Complete 20 Tasks or Mission 5 in Chapter 11 - Rise of the Serpent

Location: Times Square


Incursions: x1

Low Threat Map Icon.png Low Threats: x2
(1 point each)
Medium Threat Map Icon.png Medium Threats: x3
(2 points each)
High Threat Map Icon.png High Threats: x3
(3 points each)
Enemies
Brawler Icon.png Brawler Bruisericon.png
Passive:
Stronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damageStronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damage
Serpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and DefenseSerpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and Defense
Kunoichi Icon.png Kunoichi Infiltratoricon.png
Passive:
Bloodsense - Chance to dodge attacks from Bleeding attackersBloodsense - Chance to dodge attacks from Bleeding attackers
Serpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effectsSerpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effects
Raider Icon.png Raider Scrappericon.png
Passive:
Killer Instinct - Chance to perform a preemptive melee attack when attackedKiller Instinct - Chance to perform a preemptive melee attack when attacked
Serpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical HitsSerpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical Hits
Goliath Icon.png Goliath Bruisericon.png
Passive:
Stronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damageStronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damage
Serpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and DefenseSerpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and Defense
Chiyome Icon.png Chiyome Infiltratoricon.png
Passive:
Bloodsense - Chance to dodge attacks from Bleeding attackersBloodsense - Chance to dodge attacks from Bleeding attackers
Serpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effectsSerpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effects
Reaver Icon.png Reaver Scrappericon.png
Passive:
Killer Instinct - Chance to perform a preemptive melee attack when attackedKiller Instinct - Chance to perform a preemptive melee attack when attacked
Serpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical HitsSerpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical Hits
Behemoth Icon.png Behemoth Bruisericon.png
Passive:
Stronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damageStronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damage
Serpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and DefenseSerpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and Defense
Onna Bugeisha Icon.png Onna Bugeisha Infiltratoricon.png
Passive:
Bloodsense - Chance to dodge attacks from Bleeding attackersBloodsense - Chance to dodge attacks from Bleeding attackers
Serpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effectsSerpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effects
Marauder (Circle of 8) Icon.png Marauder Scrappericon.png
Passive:
Killer Instinct - Chance to perform a preemptive melee attack when attackedKiller Instinct - Chance to perform a preemptive melee attack when attacked
Serpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical HitsSerpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical Hits

Team-Up: Hawkeye Hawkeye (Required)

Mini-Boss
Nerkkod Icon.png Nerkkod Generalisticon.png
Passive:
Breaker of Oceans - All allies are immune to Water attacks; Chance to follow up with Rip Tide, dealing damage and applying Waterlogged; Rip Tide applies Rising TideBreaker of Oceans - All allies are immune to Water attacks; Chance to follow up with Rip Tide, dealing damage and applying Waterlogged; Rip Tide applies Rising Tide
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
Worthy - See DisambiguationWorthy - See Disambiguation
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty StaffAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Staff
Tactician Power (3 turns) - Single-target attacks grant an extra turnTactician Power (3 turns) - Single-target attacks grant an extra turn

Defeating a Mini-Boss will remove it from the full Boss battle.
Team-Up: Hellcat Hellcat (Required)
Potential Reward: Infused Iso-8

Boss + Mini-Boss
Skirn Icon.png Skirn Scrappericon.png
Passive:
Breaker of Men - All enemies gain Pain every turnBreaker of Men - All enemies gain Pain every turn
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
Worthy - See DisambiguationWorthy - See Disambiguation
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty HammerAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Hammer
Nerkkod Icon.png Nerkkod Generalisticon.png
Passive:
Breaker of Oceans - All allies are immune to Water attacks; Chance to follow up with Rip Tide, dealing damage and applying Waterlogged; Rip Tide applies Rising TideBreaker of Oceans - All allies are immune to Water attacks; Chance to follow up with Rip Tide, dealing damage and applying Waterlogged; Rip Tide applies Rising Tide
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
Worthy - See DisambiguationWorthy - See Disambiguation
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty StaffAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Staff
Tactician Power (3 turns) - Single-target attacks grant an extra turnTactician Power (3 turns) - Single-target attacks grant an extra turn


Mission 2 - Time Trials

Time Trials
S2 C12 M2.png
Team
Up:
Iconbg.pngJessica Jones Icon 1.png  Iconbg.pngSatana Icon 1.png  Iconbg.pngWasp Icon 1.png
Heroic Battle Task Icon.png Iconbg.pngUnknown Hero
Hero Deploys Iconbg.pngUnknown Hero

"The rapidly spreading fear and chaos must not slow our heroes, as they race to engage each Worthy before the Serpent may join them."
— Mission Preview

Unlock Requirements: Complete 2 Tasks

Location: Avengers Mansion


Incursions: x1

Low Threat Map Icon.png Low Threats: x2
(1 point each)
Medium Threat Map Icon.png Medium Threats: x3
(2 points each)
High Threat Map Icon.png High Threats: x2
(3 points each)
Enemies
Brawler Icon.png Brawler Bruisericon.png
Passive:
Stronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damageStronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damage
Serpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and DefenseSerpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and Defense
Kunoichi Icon.png Kunoichi Infiltratoricon.png
Passive:
Bloodsense - Chance to dodge attacks from Bleeding attackersBloodsense - Chance to dodge attacks from Bleeding attackers
Serpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effectsSerpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effects
Raider Icon.png Raider Scrappericon.png
Passive:
Killer Instinct - Chance to perform a preemptive melee attack when attackedKiller Instinct - Chance to perform a preemptive melee attack when attacked
Serpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical HitsSerpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical Hits
Goliath Icon.png Goliath Bruisericon.png
Passive:
Stronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damageStronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damage
Serpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and DefenseSerpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and Defense
Chiyome Icon.png Chiyome Infiltratoricon.png
Passive:
Bloodsense - Chance to dodge attacks from Bleeding attackersBloodsense - Chance to dodge attacks from Bleeding attackers
Serpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effectsSerpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effects
Reaver Icon.png Reaver Scrappericon.png
Passive:
Killer Instinct - Chance to perform a preemptive melee attack when attackedKiller Instinct - Chance to perform a preemptive melee attack when attacked
Serpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical HitsSerpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical Hits
Behemoth Icon.png Behemoth Bruisericon.png
Passive:
Stronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damageStronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damage
Serpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and DefenseSerpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and Defense
Onna Bugeisha Icon.png Onna Bugeisha Infiltratoricon.png
Passive:
Bloodsense - Chance to dodge attacks from Bleeding attackersBloodsense - Chance to dodge attacks from Bleeding attackers
Serpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effectsSerpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effects
Marauder (Circle of 8) Icon.png Marauder Scrappericon.png
Passive:
Killer Instinct - Chance to perform a preemptive melee attack when attackedKiller Instinct - Chance to perform a preemptive melee attack when attacked
Serpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical HitsSerpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical Hits

Team-Up: Wasp Wasp (Required)

Mini-Boss
Kuurth Icon.png Kuurth Scrappericon.png
Passive:
Breaker of Stone - All single-target attacks apply Shield Breaker; Immune to Stun and Immobilized; High chance to resist critical hitsBreaker of Stone - All single-target attacks apply Shield Breaker; Immune to Stun and Immobilized; High chance to resist critical hits
Serpent Spider Serum - Immune to Poisoned, Radiation, and Bio effects; Immune to Psychic and Delirium effectsSerpent Spider Serum - Immune to Poisoned, Radiation, and Bio effects; Immune to Psychic and Delirium effects
Worthy - See DisambiguationWorthy - See Disambiguation
Worthy Vengeance - 50% chance to counter Melee attacks with Stonebreaker; 50% chance to counter Ranged attack with Road to RuinWorthy Vengeance - 50% chance to counter Melee attacks with Stonebreaker; 50% chance to counter Ranged attack with Road to Ruin
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty DaggerAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Dagger

Team-Up: Jessica Jones Jessica Jones (Required)

Mini-Boss
Nul Icon.png Nul Bruisericon.png
Passive:
Breaker of Worlds - Attacks have a chance to apply Meteor Swarm on attacks; Gain a stack of Divine Hammer each roundBreaker of Worlds - Attacks have a chance to apply Meteor Swarm on attacks; Gain a stack of Divine Hammer each round
Prove Your Worth - Intercepts single-target attacks by Unworthy enemies; Preemptively counters Unworthy enemiesProve Your Worth - Intercepts single-target attacks by Unworthy enemies; Preemptively counters Unworthy enemies
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
Worthy - See DisambiguationWorthy - See Disambiguation
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty MaceAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Mace

Defeating a Mini-Boss will remove it from the full Boss battle.
Team-Up: Satana Satana (Required)
Potential Reward: Infused Iso-8

Boss + Mini-Boss
Angrir Icon.png Angrir Infiltratoricon.png
Passive:
Breaker of Souls - Gains Infernal Power when an enemy is defeatedBreaker of Souls - Gains Infernal Power when an enemy is defeated
Lost Darksoul - Restores Health after attacking; Counters Fire and Magic attacks; Chance to nullify damage from enemy Magic attacks against all allies; Restores Stamina after nullifying a Magic attackLost Darksoul - Restores Health after attacking; Counters Fire and Magic attacks; Chance to nullify damage from enemy Magic attacks against all allies; Restores Stamina after nullifying a Magic attack
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
Worthy - See DisambiguationWorthy - See Disambiguation
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty TridentAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Trident
Kuurth Icon.png Kuurth Scrappericon.png
Passive:
Breaker of Stone - All single-target attacks apply Shield Breaker; Immune to Stun and Immobilized; High chance to resist critical hitsBreaker of Stone - All single-target attacks apply Shield Breaker; Immune to Stun and Immobilized; High chance to resist critical hits
Serpent Spider Serum - Immune to Poisoned, Radiation, and Bio effects; Immune to Psychic and Delirium effectsSerpent Spider Serum - Immune to Poisoned, Radiation, and Bio effects; Immune to Psychic and Delirium effects
Worthy - See DisambiguationWorthy - See Disambiguation
Worthy Vengeance - 50% chance to counter Melee attacks with Stonebreaker; 50% chance to counter Ranged attack with Road to RuinWorthy Vengeance - 50% chance to counter Melee attacks with Stonebreaker; 50% chance to counter Ranged attack with Road to Ruin
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty DaggerAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Dagger
Nul Icon.png Nul Bruisericon.png
Passive:
Breaker of Worlds - Attacks have a chance to apply Meteor Swarm on attacks; Gain a stack of Divine Hammer each roundBreaker of Worlds - Attacks have a chance to apply Meteor Swarm on attacks; Gain a stack of Divine Hammer each round
Prove Your Worth - Intercepts single-target attacks by Unworthy enemies; Preemptively counters Unworthy enemiesProve Your Worth - Intercepts single-target attacks by Unworthy enemies; Preemptively counters Unworthy enemies
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
Worthy - See DisambiguationWorthy - See Disambiguation
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty MaceAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Mace


Mission 3 - Serpent Strike

Serpent Strike
S2 C12 M3.png
Team
Up:
Iconbg.pngCaptain America Icon 1.png  Iconbg.pngDr. Strange Icon 1.png  Iconbg.pngFaiza Hussain Icon 1.png
Iconbg.pngIron Man Icon 1.png  Iconbg.pngThor Icon 1.png  Iconbg.pngThor (Jane Foster) Icon 1.png
Heroic Battle Task Icon.png Iconbg.pngUnknown Hero
Hero Deploys Iconbg.pngUnknown Hero

"The Serpent has arrived! It is time to strike a Mighty blow or face inescapable doom. The fate of Midgard hangs in the balance."
— Mission Preview

Unlock Requirements: Complete 5 Tasks

Location: Avengers Tower


Incursions: x1

Low Threat Map Icon.png Low Threats: x2
(1 point each)
Medium Threat Map Icon.png Medium Threats: x3
(2 points each)
High Threat Map Icon.png High Threats: x2
(3 points each)
Enemies
Brawler Icon.png Brawler Bruisericon.png
Passive:
Stronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damageStronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damage
Serpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and DefenseSerpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and Defense
Kunoichi Icon.png Kunoichi Infiltratoricon.png
Passive:
Bloodsense - Chance to dodge attacks from Bleeding attackersBloodsense - Chance to dodge attacks from Bleeding attackers
Serpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effectsSerpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effects
Raider Icon.png Raider Scrappericon.png
Passive:
Killer Instinct - Chance to perform a preemptive melee attack when attackedKiller Instinct - Chance to perform a preemptive melee attack when attacked
Serpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical HitsSerpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical Hits
Goliath Icon.png Goliath Bruisericon.png
Passive:
Stronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damageStronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damage
Serpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and DefenseSerpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and Defense
Chiyome Icon.png Chiyome Infiltratoricon.png
Passive:
Bloodsense - Chance to dodge attacks from Bleeding attackersBloodsense - Chance to dodge attacks from Bleeding attackers
Serpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effectsSerpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effects
Reaver Icon.png Reaver Scrappericon.png
Passive:
Killer Instinct - Chance to perform a preemptive melee attack when attackedKiller Instinct - Chance to perform a preemptive melee attack when attacked
Serpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical HitsSerpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical Hits
Behemoth Icon.png Behemoth Bruisericon.png
Passive:
Stronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damageStronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damage
Serpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and DefenseSerpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and Defense
Onna Bugeisha Icon.png Onna Bugeisha Infiltratoricon.png
Passive:
Bloodsense - Chance to dodge attacks from Bleeding attackersBloodsense - Chance to dodge attacks from Bleeding attackers
Serpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effectsSerpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effects
Marauder (Circle of 8) Icon.png Marauder Scrappericon.png
Passive:
Killer Instinct - Chance to perform a preemptive melee attack when attackedKiller Instinct - Chance to perform a preemptive melee attack when attacked
Serpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical HitsSerpentine Scrapper - Removed by Mighty Weapons or Mighty Means; Prevents effects that Lockout Melee attacks; Immune to Winded; Performing a follow-up attack increases Attack and chance for Critical Hits

Team-Up: Dr. Strange Dr. Strange (Required)

Mini-Boss
Greithoth Icon.png Greithoth Blastericon.png
Passive:
Breaker of Wills - Chance to preemptively counter with Cower and Agony; Halves damage from non-Hallowed attacksBreaker of Wills - Chance to preemptively counter with Cower and Agony; Halves damage from non-Hallowed attacks
Eye of the Serpent - Preemptively counter enemy attacks with Sin; 50% Chance to survive being KO'ed from an attackEye of the Serpent - Preemptively counter enemy attacks with Sin; 50% Chance to survive being KO'ed from an attack
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
Worthy - See DisambiguationWorthy - See Disambiguation
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty SkullAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Skull

Team-Up: Faiza Hussain Faiza Hussain (Required)

Mini-Boss
Mokk Icon.png Mokk Bruisericon.png
Passive:
Blood Oath - Chance to perform a follow-up attack when an ally attacks a Bleeding target; Chance to counter when a Bleeding enemy attacks an allyBlood Oath - Chance to perform a follow-up attack when an ally attacks a Bleeding target; Chance to counter when a Bleeding enemy attacks an ally
Breaker of Faith - Grants all allies Magic Warding; Chance to parry and absorb an attack then perform a counter-attackBreaker of Faith - Grants all allies Magic Warding; Chance to parry and absorb an attack then perform a counter-attack
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
Worthy - See DisambiguationWorthy - See Disambiguation
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty SwordAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Sword

Team-Up: Captain America Captain America (Required)

Mini-Boss
Skadi Icon.png Skadi Blastericon.png
Passive:
Aura of Fear - Chance to Apply CowerAura of Fear - Chance to Apply Cower
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
Worthy - See DisambiguationWorthy - See Disambiguation
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty AxeAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Axe

Defeating a Mini-Boss will remove it from the full Boss battle.
Team-Up: Thor Thor (Required), Thor (Jane Foster) Thor (Jane Foster) (Required)
Potential Reward: Infused Iso-8

Boss + Mini-Boss
Wave 1
Greithoth Icon.png Greithoth Blastericon.png
Passive:
Breaker of Wills - Chance to preemptively counter with Cower and Agony; Halves damage from non-Hallowed attacksBreaker of Wills - Chance to preemptively counter with Cower and Agony; Halves damage from non-Hallowed attacks
Eye of the Serpent - Preemptively counter enemy attacks with Sin; 50% Chance to survive being KO'ed from an attackEye of the Serpent - Preemptively counter enemy attacks with Sin; 50% Chance to survive being KO'ed from an attack
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
Worthy - See DisambiguationWorthy - See Disambiguation
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty SkullAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Skull
Mokk Icon.png Mokk Bruisericon.png
Passive:
Blood Oath - Chance to perform a follow-up attack when an ally attacks a Bleeding target; Chance to counter when a Bleeding enemy attacks an allyBlood Oath - Chance to perform a follow-up attack when an ally attacks a Bleeding target; Chance to counter when a Bleeding enemy attacks an ally
Breaker of Faith - Grants all allies Magic Warding; Chance to parry and absorb an attack then perform a counter-attackBreaker of Faith - Grants all allies Magic Warding; Chance to parry and absorb an attack then perform a counter-attack
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
Worthy - See DisambiguationWorthy - See Disambiguation
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty SwordAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Sword
Onna Bugeisha Icon.png Onna Bugeisha Infiltratoricon.png
Passive:
Bloodsense - Chance to dodge attacks from Bleeding attackersBloodsense - Chance to dodge attacks from Bleeding attackers
Serpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effectsSerpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effects
Wave 2
Goliath Icon.png Goliath Bruisericon.png
Passive:
Stronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damageStronghold (2 rounds) - Chance to protect allies from single-target attacks; Takes reduced damage
Serpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and DefenseSerpentine Bruiser - Removed by Mighty Weapons or Mighty Means; Immune to Cornered; Drains Health and Stamina from attackers when attacked by non-psychic, melee attacks; Immune to Neutralized; Gains Serpentine Strength when hit, increasing Attack and Defense
Skadi Icon.png Skadi Blastericon.png
Passive:
Aura of Fear - Chance to Apply CowerAura of Fear - Chance to Apply Cower
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
Worthy - See DisambiguationWorthy - See Disambiguation
Aura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty AxeAura of the Serpent - Applies Paralyzing Fear and Terrified to attackers; Removed by the Iso-Infused Mighty Axe
Chiyome Icon.png Chiyome Infiltratoricon.png
Passive:
Bloodsense - Chance to dodge attacks from Bleeding attackersBloodsense - Chance to dodge attacks from Bleeding attackers
Serpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effectsSerpentine Infiltrator - Removed by Mighty Weapons or Mighty Means; Immune to Off-balance; The Counter-Attack from Combat Reflexes is now a Preemptive Counter-Attack; Counter-Attacks gain Ignore Defense, ignoring the Defense stat and penetrating Shield effects
Wave 3
Cul Borson Icon.png Cul Borson Tacticianicon.png
Passive:
Asgardian - Immune to Burning, Chilled, Poison, and RadiationAsgardian - Immune to Burning, Chilled, Poison, and Radiation
Feeds on Fear - Immune to interrupt and fear effectsFeeds on Fear - Immune to interrupt and fear effects
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects

Requires completion of all Battles and Deploys.
Team-Up: Iron Man Iron Man (Required)
Potential Reward: Infused Iso-8

Epic Boss
Wave 1
Odin Icon.png Odin Generalisticon.png
Passive:
Asgardian - Immune to Burning, Chilled, Poison, and RadiationAsgardian - Immune to Burning, Chilled, Poison, and Radiation
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
So Predictable... - Immune to InterruptsSo Predictable... - Immune to Interrupts
Strengthened Haste - Taking three actions every roundStrengthened Haste - Taking three actions every round
Wave 2
Odin Icon.png Odin Generalisticon.png
Passive:
Asgardian - Immune to Burning, Chilled, Poison, and RadiationAsgardian - Immune to Burning, Chilled, Poison, and Radiation
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
So Predictable... - Immune to InterruptsSo Predictable... - Immune to Interrupts
Strengthened Haste - Taking three actions every roundStrengthened Haste - Taking three actions every round
Wave 3
Odin Icon.png Odin Generalisticon.png
Passive:
Asgardian - Immune to Burning, Chilled, Poison, and RadiationAsgardian - Immune to Burning, Chilled, Poison, and Radiation
Relentless - Immune to Stun, Exhaustion, Cower and prevention effectsRelentless - Immune to Stun, Exhaustion, Cower and prevention effects
So Predictable... - Immune to InterruptsSo Predictable... - Immune to Interrupts
World Ravager (4 turns) - Odin is preparing for a powerful attack that will KO any heroes that are too weakWorld Ravager (4 turns) - Odin is preparing for a powerful attack that will KO any heroes that are too weak
Strengthened Haste - Taking three actions every roundStrengthened Haste - Taking three actions every round


Chapter Mastery

Mastering the Chapter grants various rewards. No Heroes are required for this chapter mastery.

Restricted Heroes

The following Heroes are unavailable due to mission restrictions.

Mission 1 & Mission 2
Black Knight Icon Large 1.png Daimon Hellstrom Icon Large 1.png Ghost Rider Icon Large 1.png Luke Cage Icon Large 1.png Mockingbird Icon Large 1.png She-Hulk Icon Large 1.png Spider-Woman Icon Large 1.png
Mission 3
Black Knight Icon Large 1.png Daimon Hellstrom Icon Large 1.png Ghost Rider Icon Large 1.png Luke Cage Icon Large 1.png Mockingbird Icon Large 1.png
She-Hulk Icon Large 1.png Spider-Woman Icon Large 1.png Thor Icon Large 1.png Thor (Jane Foster) Icon Large 1.png



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