After suffering three defeats in a row from the wall crawling, web-slinging superhero Spider-Man, Doctor Octopus realized he required assistance from others in order to defeat Spider-Man. He got in touch with every known super-villain Spider-Man had crossed paths with and only five responded: the airborne assassin the Vulture, the electrifying Electro, the wild Kraven the Hunter, the mysterious master of illusions Mysterio and the shape-shifting Sandman. Knowing he'd never be able to keep the team together for long, Doctor Octopus quickly formulated a battle plan that would give each of the villains personal glory and Spider-Man an early death. Each individual member of the Sinister Six would battle Spider-Man in a carefully chosen location, until the point where the wall-crawler was no more.
In-Game Members[]
Heroes[]
 As Venom |
 Formerly |
 Leader |
 |
 |
 |
 Formerly |
 |
 (Doctor Octopus) Former Leader |
Villains[]
 Anti-Venom As Venom |
 Beetle Formerly |
 Boomerang Leader |
 Doctor Octopus Former Leader |
 Electro |
 Green Goblin |
 Grim Reaper |
 Hammerhead |
 Hydro-Man |
 Kraven |
 Lizard |
 Mysterio as Quentin Beck |
 Sandman Formerly |
 Shocker Former Leader |
 The Owl |
 Venom Eddie Brock (Sandman's Sinister Six) MacDonald Gargan (Sinister Twelve) |
 Vulture |
Effects[]
Sinister Six Effects[]
| Name | Name | Name |
|---|---|---|
  Electro |
Kraven |
Lizard |
Mysterio |
Vulture |
Doctor Octopus |
Team-Up Bonuses[]
| Sinister Six | Former Members of the Sinister Six |
|
| Superior Foes | Current or former members of the Superior Foes of Spider-Man |
|
External Links[]
- Sinister Six on Wikipedia
- Sinister Six at the Marvel Comics Database Wiki